2-Cyano-3-[3,4-dihydroxyphenyl]-N-[phenylmethyl]-2-propenamide; Tyrphostin AG 490
A potent and specific inhibitor of the JAK-2 tyrosine kinese. In acute lymphoblastic leukemia (ALL) cells which abundantly express JAK-2, AG-490 dose-dependently inhibited DNA synthesis, blocked cell growth and induced papooses. AG-490 does not significan
Chemical Formula |
C17H14N2O3 |
Molecular Weight |
F.W. 294.30 |
CAS # |
134036-52-5 |
Safety Information |
|
Health Hazard |
2 |
Fire Hazard |
1 |
Reactivity |
0 |
Test |
Specification |
Appearance | Pale yellow-green crystal |
Melting Point | 213°C |
Storage Information |
DEEP FREEZE: Keep tightly closed. |
Chemical information and descriptions have been provided by Spectrum Chemicals.