(+)-Amethopterin; 4-Amino-10-methylfolic Acid
Used as an inhibitor of dihydrofolate reductase, and as an agent for antitumor studies.
Antineoplastic, antirheumatic.
Chemical Formula |
C20H22N8O5 |
Molecular Weight |
F.W. 454.44 |
CAS # |
59-05-2 |
Safety Information |
|
Health Hazard |
2 |
Fire Hazard |
1 |
Reactivity |
0 |
Test |
Specification |
Assay (C20H22N8O5; Anhydrous Basis) | 98.0-102.0% |
Specific Rotation | +19° to +24° |
Chromatographic Purity | To pass test |
MAXIMUM LIMITS | |
Water | 12.0% |
Residue on Ignition | 0.1% |
Organic Volatile Impurities | To pass test |
Shipping Information |
Toxic solid, organic, n.o.s. (methotrexate), 6.1, UN2811, PG III. Additional UPS-imposed hazardous material charge. |
UPS limit |
70 lb |
Storage Information |
LIGHT SENSITIVE: Keep tightly closed in light-resistant containers. |
Chemical information and descriptions have been provided by Spectrum Chemicals.