Methotrexate, USP

(+)-Amethopterin; 4-Amino-10-methylfolic Acid

 

Used as an inhibitor of dihydrofolate reductase, and as an agent for antitumor studies.
Antineoplastic, antirheumatic.

 

Chemical Formula

C20H22N8O5

Molecular Weight

F.W. 454.44

CAS #

59-05-2

 

Safety Information

Health Hazard

2

Fire Hazard

1

Reactivity

0

Material Safety Data Sheet

 

Test

Specification

Assay (C20H22N8O5; Anhydrous Basis)98.0-102.0%
Specific Rotation+19° to +24°
Chromatographic PurityTo pass test
MAXIMUM LIMITS
Water12.0%
Residue on Ignition0.1%
Organic Volatile ImpuritiesTo pass test

 

Shipping Information

Toxic solid, organic, n.o.s. (methotrexate), 6.1, UN2811, PG III. Additional UPS-imposed hazardous material charge.

UPS limit

70 lb

Storage Information

LIGHT SENSITIVE: Keep tightly closed in light-resistant containers.

Chemical information and descriptions have been provided by Spectrum Chemicals.

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 M1435-01   Methotrexate, USP - Methotrexate, USP - C20H22N8O5 - 1 GM M1435-01 $2,060.51
 M1435-OK   Methotrexate, USP - Methotrexate, USP - C20H22N8O5 - 100 MG M1435-OK $350.61
 M1435-ON   Methotrexate, USP - Methotrexate, USP - C20H22N8O5 - 250 MG M1435-ON $531.08
 M1435-02   Methotrexate, USP - Methotrexate, USP - C20H22N8O5 - 5 GM M1435-02 $6,417.19
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